James Fadiman, a pioneer of psychedelic research, developed this widely used schedule:
James Fadiman, a pioneer of psychedelic research, developed this widely used schedule:
- Day 1: Microdose
- Day 2: No microdosing (after-effects)
- Day 3: No microdosing (normal condition)
- Day 4: Microdose
This cycle is repeated two to three times a week. There should be enough time between doses to avoid tolerance.
2nd Stamets Stack (Paul Stamets)
Paul Stamets, a mycologist, has developed a protocol that combines microdosing with psilocybin, niacin (vitamin B3) and lion’s mane mushroom. His scheme often looks like this:
- 4 days microdosing, then 3 days break. The lion’s mane mushroom is said to improve cognitive functions, while niacin is said to promote blood circulation and distribute the psilocybin more efficiently in the body.
3. 5 days up, 2 days down
This involves taking a microdose on five consecutive days, followed by two days off. This routine can be useful in working environments as it covers the entire working period and keeps the weekend free for regeneration.
4. every third day
You take a microdose every third day. This is an alternative to the Fadiman protocol, but offers more flexibility for people who prefer different types of substances or different schedules.
5. once a week
For those looking for a gentle but regular effect without a long-term commitment, microdosing once a week can be a sustainable option.
Important notes:
- Dosage: The microdose is usually around 5-10% of the usual psychedelic dose. For LSD this means about 10-20 micrograms, and for psilocybin about 0.1-0.3 grams of dried mushrooms.
- Take breaks: Regular breaks are important to avoid tolerance build-up and to protect the body.
- Self-reflection: It is recommended to keep a diary to record the effect on mood, creativity, concentration or anxiety.
Microdosing should always be approached with caution, especially in countries where psychedelic substances are illegal.
